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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
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Meso Scale Discovery offers the V-PLEX NHP Cytokine Panel 30-Plex Kit for the quantitative measurement of 30 non-human primate cytokines chemokines and growth factors This multiplex assay allows researchers to measure biomarkers from small sample volumes with high sensitivity and broad dynamic range The kit includes a 30-plex primate panel calibrators controls detection antibodies read buffer sample diluent and plates It utilizes electrochemiluminescence technology on Meso Scale Discovery s instrumentation platforms for high performance immunoassays This product enables efficient analysis of NHP biomarkers relevant to modeling human diseases
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The SARS-CoV-2 Panel 2 (ACE2) is a multiplex immunoassay panel from Meso Scale Diagnostics that detects antibodies to the SARS-CoV-2 spike and nucleocapsid proteins as well as the ACE2 receptor It uses electrochemiluminescence detection technology and provides quantitative results from human serum plasma or whole blood samples The panel includes reagents for 96 tests and can help evaluate immune responses in COVID-19 vaccine studies and natural infection It has high sensitivity and specificity and has received Emergency Use Authorization from the FDA
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The V-PLEX Plus Metabolic Panel 1 Rat Kit from Meso Scale Discovery is a multiplex immunoassay kit that allows simultaneous measurement of 10 metabolic biomarkers in rat serum plasma and tissue culture media The kit includes a 96-well plate pre-coated with capture antibodies for insulin leptin amylin GLP-1 PYY ghrelin GIP C-peptide glucagon and resistin It utilizes electrochemiluminescence detection and provides high sensitivity broad dynamic range and requires low sample volume This kit allows efficient metabolic profiling and is suitable for studying diabetes obesity and metabolic disorders in rat models
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The Meso Scale Discovery V-PLEX Orthopoxvirus Panel 1 IgG Kit is an electrochemiluminescence immunoassay that detects IgG antibodies to vaccinia virus monkeypox virus cowpox virus and ectromelia virus in serum and plasma samples This multiplex assay uses MSD s proprietary SULFO-TAG labels and multi-array technology to provide quantitative results with high sensitivity and dynamic range The kit includes a 96-well plate coated with antigens detection antibodies calibrators controls diluent wash buffer read buffer and plate seals This assay can aid in evaluating orthopoxvirus exposure and immune response
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The Meso Scale Diagnostics SARS-CoV-2 Panel 1 IgG is an immunoassay test kit that detects IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology on Meso Scale Diagnostics proprietary multi-array plate platform The test kit includes a 96-well plate coated with SARS-CoV-2 antigens detection antibodies calibrators controls diluent and wash buffer Results are obtained in under 3 hours using Meso Scale Diagnostics MESO QuickPlex SQ 120 instrument This semi-quantitative test can aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection
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12(S)-hydroxy-16-Heptadecynoic acid is a mechanism-based inhibitor of CYP450 W-hydroxylase.{1051} It inhibits prostaglandin W-hydroxylase with a Ki value of 1.8 UM.{1051}
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The Mesoscale K15482U-4 is a 4-channel low noise amplifier with a frequency range of 10 MHz to 8 GHz It provides a gain of 20 dB and noise figure of 0 8 dB The amplifier has an input P1dB of 13 dBm and output P1dB of 21 dBm It operates on a single 5V supply and draws 285 mA of current The amplifier comes in a surface mount 4x4 mm QFN package Key features include wideband performance low noise figure high linearity and a compact footprint
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The V-PLEX COVID-19 Respiratory Panel 3 IgG Kit from Meso Scale Diagnostics is an immunoassay that detects IgG antibodies to SARS-CoV-2 in human serum and plasma This qualitative assay uses an electrochemiluminescence detection method and provides results in under 3 hours The kit includes reagents for 96 tests and has 100% sensitivity and 99 6% specificity It is intended for use as an aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection
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Meso Scale Discovery offers a variety of assay kits that enable detection of biomarkers immunogenicity and pharmacodynamic readouts using electrochemiluminescence technology The kits include all necessary reagents and plates for running immunoassays and cell-based assays to measure protein biomarkers cytokines phosphorylation events and other analytes from biological samples Key features of the kits include high sensitivity broad dynamic range and minimal sample volume requirements The kits are available in multiplex and singleplex formats to enable simultaneous detection of multiple analytes from a single sample
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The Mesoscale K15619U-2 is a high-performance thermoelectric module that can be used for cooling heating and temperature control applications It consists of 127 thermocouples made from Bismuth Telluride semiconductor material sandwiched between two ceramic substrates Key features include a maximum temperature difference of 69 C an operating current of 3 4 Amps and dimensions of 40 x 40 x 3 4mm With a high coefficient of performance this Peltier module can provide efficient and precise temperature control for small spaces The K15619U-2 requires a heat sink and fan for heat dissipation
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Meso Scale Discovery offers a wide variety of V-PLEX assay kits for measuring biomarkers in mouse samples The electrochemiluminescent immunoassays provide high sensitivity broad dynamic range and low sample volume requirements Kits are available for measuring cytokines chemokines growth factors soluble receptors and other analytes in mouse serum plasma cell culture supernatants and other sample types The V-PLEX platform enables multiplex analysis of up to 10 biomarkers per well from a single small-volume sample
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The Mesoscale K15625U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition system It features 4 analog input channels with software-selectable input ranges of 10 V 5 V 2 V and 1 V The system has 16-bit resolution 250 kS/s maximum aggregate sample rate and includes anti-aliasing filters It connects to a host computer via USB 2 0 interface and is compatible with Windows operating systems The compact device is bus-powered
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The Mesoscale K15611U-2 is a high-performance thermoelectric cooler designed for precision temperature control applications It measures 40 x 40 x 3 4mm and provides a maximum heat pumping capacity of 15W at 27 C temperature difference This Peltier cooler has a no load voltage of 15 4V and can achieve a maximum temperature difference of 70 C It is constructed using Bismuth Telluride semiconductor material sandwiched between two ceramic plates With a high coefficient of performance and compact design this thermoelectric module is well-suited for stabilizing the operating temperature of sensitive electronic components and optical devices
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The Meso Scale Discovery V-PLEX Human Pro-Inflammatory Panel 1 (4-Plex) is an electrochemiluminescent multiplex assay kit for quantifying four pro-inflammatory biomarkers IFN- IL-1 IL-6 and TNF- in human samples It uses MSD s multi-array technology for sensitive reproducible results with higher throughput than ELISA The V-PLEX assays run on MSD s SECTOR Imager reading up to 96 wells The kit includes a plate with capture antibodies detection antibodies calibrators controls diluent wash buffer read buffer and plate seals for one 96-well plate
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The Meso Scale Discovery V-PLEX Viral Panel 2 Human Kit is a multiplex immunoassay that simultaneously detects antibodies to SARS-CoV-2 Influenza A Influenza B and RSV in human serum and plasma This assay uses electrochemiluminescence detection technology and provides quantitative results in under 3 hours The kit includes a 96-well plate coated with antigens detection antibodies calibrators controls wash buffer read buffer and plate seals This assay allows high-throughput sensitive and accurate serological testing for four common respiratory viruses
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